Master Equations

Relation between IFCC numbers and the respective national DCMs

The relations can be expressed either as conversion formulas or as
HbA1c numbers at given clinical conditions.

Conversion factors

National DCM From IFCC to DCM From DCM to IFCC
NGSP (USA) NGSP = 0.09148 IFCC + 2.152 IFCC = 10.93 NGSP - 23.50
JDS/JSCC (Japan) JDS = 0.09274 IFCC + 1 .724 IFCC = 10.78 JDS - 18.59
Mono-S (Sweden) Mono-S = 0.09890 IFCC + 0.884 IFCC = 10.11 Mono-S - 8.94

 

Source: Hoelzel W, Weykamp C, Jeppsson JO, Miedema K, Barr JR, Goodall I, Hoshino T, John WG, Kobold U, Little R, Mosca A, Mauri P, Paroni R, Susanto F, Takei I, Thienpont L, Umemoto M, Wiedmeyer HM. IFCC Reference System for Measurement of Hemoglobin A1c in human blood and the national standardization schemes in the United States, Japan and Sweden: a method comparison study.
Clin.Chem. 2004; 50: 166-174

 

Published Clinical Targets and Reference Ranges, expressed in IFCC and DCM numbers, respectively

Clinical Condition IFCC NGSP JDS/JSCC Mono-S
Upper level of non-diabetic reference range 43 mmol/mol 6.1 % 5.7 % 5.1 %
ADA target for patients with diabetes  53 mmol/mol 7.0 % 6.6 % 6.1 %